The MOG Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MOG. This antibody recognizes Human, Mouse, and Rat antigen. The MOG Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Description: The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
Function: Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
Subunit Structure: Homodimer (By similarity). May form heterodimers between the different isoforms (By similarity).
Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family